![]() ![]() Spike Essential replaces 45300 WeDo 2.0 Core Set (2016), 224. For older kids, Spike Prime replaces 45544 EV3 Core Set (2013), 340. This review gave me a chance to take closer look closer at the two parts which are unique to this set, the smaller 2-port Intelligent Hub, and the 3×3 Color LED Matrix display. WeDo 2.0 replaced the WeDo 1.0 product, which was introduced in 2009. WeDo 2.0 targeted a slightly smaller age group of grades 2-4. WeDo 2.0 was released at the beginning of 2016. The original WeDo set was released in 2009. The app features support for a variety of different video formats, including mp4, mkv, avi, and a lot more. LEGO item numbers NA: 6257295 EU: 6138600 Availability Educational Notes Common season-to-season baseline of parts for FIRST LEGO League Explore (formerly known as FIRST LEGO League Jr.) between 21. For younger kids, Spike Essential replaces 45300 WeDo 2.0 Core Set (2016), 224. Posted by Wayne Burnett WeDo Getting Started LEGO WeDo is a robotics kit designed for younger students. ![]() VLCĭid you know that the popular VLC media player is also available as a Windows 10 UWP app? Well, it is and it looks a whole lot better than the desktop version – that’s one reason why you should get it right away. Wildlife Crossing Love using WeDo 2.0 Learn more about our next generation product, LEGO ® Education SPIKE Essential. The LEGO EDUCATION WeDo 2.0 robots may not be a type of robots that will go buy the breakfast every day or take care of your grandfather, but it could teach many things that will help you in your life from computational thinking to building LEGO models. ![]()
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![]() ![]() The emetic response to chemotherapy is now thought to occur through both a peripheral and a central pathway. Several neurotransmitters, including dopamine, serotonin (5-HT), and substance P, are now well established as important mediators of CINV. Not only can CINV have a detrimental effect on patients’ quality of life, but it can also lead to chemotherapy dose reductions or discontinuation, thereby negatively impacting a patient’s response to treatment.Īdvances over the past three decades have not only helped elucidate mechanisms by which chemotherapeutic agents induce nausea and vomiting, but the American Society of Clinical Oncology (ASCO) has recognized the development of effective antiemetic therapies among the top five advances in oncology over the last 50 years. Ĭhemotherapy-induced nausea and vomiting (CINV) is a common distressing side effect associated with many chemotherapeutic drugs and regimens. To view digital features for this article go to. This article is published with digital features, including an infographic, to facilitate understanding of the article. It may be prudent for clinicians to continue to assess these symptoms beyond the traditional 5-day period after cisplatin-based chemotherapy. ![]() This exploratory analysis utilized a last observation carried forward (LOCF) approach for missing values for the complete response evaluation.Ĭomplete response rates were numerically higher for fosnetupitant than fosaprepitant during all time intervals and significantly higher for fosnetupitant in the extended overall 0–168 h phase. The primary analysis of this study (previously published) showed non-inferiority of fosnetupitant and fosaprepitant for overall 0–120 h complete response (no emetic event and no rescue medication) rates. fosaprepitant) antiemetic regimens beyond the 120 h time point for prevention of cisplatin-based highly emetogenic CINV. This was the first study to compare two neurokinin 1 (NK 1) receptor antagonist (RA)-containing (fosnetupitant vs. InfographicĬhemotherapy-induced nausea and vomiting (CINV) is described as occurring in two arbitrarily defined phases: the acute phase (from 0 to 24 h following chemotherapy initiation) and the delayed phase (from 24 h to 120 h), with almost all antiemetic studies evaluating treatment efficacy only to 120 h after the administration of chemotherapy. In this exploratory analysis, fosnetupitant appeared to be more effective than fosaprepitant in preventing CINV associated with cisplatin-based HEC during the extended 7-day period following chemotherapy. Complete response rates were numerically higher for fosnetupitant versus fosaprepitant for all time intervals and statistically significant for the extended overall phase. Complete response rates for fosnetupitant versus fosaprepitant during the overall, acute, delayed, extended delayed, beyond delayed, and extended overall phases were 75.5% vs. ResultsĪ total of 785 patients were included (fosnetupitant N = 392, fosaprepitant N = 393). Complete response rates were calculated and compared (stratified by age category and sex with a Mantel–Haenszel test) during the study’s primary overall phase (0–120 h) and during additional time intervals of interest. Patients scheduled to receive cisplatin-based chemotherapy were randomized 1:1 to fosnetupitant 235 mg or fosaprepitant 150 mg in combination with PALO 0.75 mg and DEX. ![]() This analysis was performed to validate the findings of the primary analysis (previously published) utilizing a last observation carried forward (LOCF) approach for missing values for the efficacy endpoint of complete response (no emetic event and no rescue medication), while also evaluating the time periods encompassing the 0–168-hour (h) “extended overall phase” interval. We describe the results of an exploratory analysis performed on the first head-to-head study (JapicCTI-194611) comparing two different intravenous (IV) neurokinin 1 (NK 1) receptor antagonists, fosnetupitant and fosaprepitant, in combination with palonosetron (PALO) and dexamethasone (DEX) for the prevention of highly emetogenic chemotherapy (HEC)-induced nausea and vomiting (CINV). ![]() ![]() ![]() YourUsername will be your userid so it will be different. Near the top of the list you'll see one that looks like APPDATA=C:\documents and settings\ YourUsername\Application Data. This will give you a list of all the environment variables that your session has set. Once the box opens just type the word set and press enter. To check it open a command prompt window (old style dos box).click on start, click on run and then type cmd and press enter. [ I have tried this configuration with FLC several times on my Windows 10 and never worked.In XP the 'appdata' setting is under documents and settings. To make things easier, we would like to recommend to you several other programs that can also help you watch a Blu-ray movie on your computer more easily in the below content. While it is not the most complicated way to play Blu-ray with VLC, it does take time to read and follow the steps. Step 7: Finally, you can easily play Blu-ray on VLC media player. Paste and drop AACS Dynamic library file in this folder. Go to C drive and find “Video LAN > VLC” in the program files of 32 bit. Step 6: Download and install AACS DYNAMIC LIBRARY in the computer. C: USERS>”User Name”>Right-Click>Properties>Hidden>Apply>All Files>Any Authorizations (if needed) (repeat) Right-Click>Properties>Hidden>Apply>All Files>any A\authorizations (if needed) Step 5: User needs to make a new folder in the App data that is called AACS and paste the downloaded KEYDB.cfg key file in the new folder. Step 3: Open the user area “C:\Users\your username\AppData.” Step 4: Under Folder Options > View tab, then select “show hidden files…”>select “OK” button. Download 32-bit files for 32-bit VLC, and 64-bit files for 64-bit VLC. Step 2: Go to URL and download KEYS DATABASE (KEYDB.cfg) and AACS DYNAMIC LIBRARY. Step 1: Visit and download the latest version of VLC media player on your computer. Below we will show you the method on how to play Blu-ray on VLC on Windows 11,10,8 ![]() ![]() Housing Market Nightmare Is About to Get Worse While his age concerns Williamson, she says she doesn’t have "any interest in personalizing my opposition to President Biden.” Williamson, currently polling last among Democratic candidates, told Newsweek that her aim is "convincing those who don't even have enough hope left to try once more, and give the Democrats a chance.” ![]() history, will turn 82 just weeks after the 2024 election and would be 86 by the end of a potential second term. A recent poll from ABC News and The Washington Post found that 68% of Americans believe Biden is too old to serve a second term as president.īiden, already the oldest president in U.S. politicians-laid bare by the California Senator Dianne Feinstein's health-related absence from Congress-has prompted debate on introducing term limits or even a maximum age for lawmakers. In an interview with Newsweek, Williamson said if Biden is selected to run against the GOP candidate-most likely former President Donald Trump- Democrats will end up "watching a slow-motion car crash reminiscent of 2016." Williamson, the author who unexpectedly became the darling of a small faction of progressive Democrats when she ran for president in 2020, is once again running for the 2024 Democratic nomination. ![]() Marianne Williamson called President Joe Biden "selfish" for seeking a second term due to his age. "People who think that are enough, for the most part, tend to be people who already have adequate healthcare, and can afford to send their kids to college and are not loaded down by crippling medical debt or college loan debt,” Marianne Williamson told Newsweek. Joe Biden is 'Selfish' to be Running at His Age-Marianne Williamson We appreciate your feedback and you starting your day with us. ![]() If you have any story tips, feedback or ideas for what we should do next, please email Emeri B. If you've been forwarded this email, you can sign up on /newsletter. If you like this newsletter, please share it. The group met with Ukrainian President Volodymyr Zelensky and is scheduled to meet with Russian President Vladimir Putin in St. In the ongoing war in Ukraine, Russian missiles hit Kyiv as a group of African leaders arrived for peace talks.Vegas Golden Knights fans will celebrate the team's first Stanley Cup win with a parade down the Las Vegas Strip tonight.The WNBA is working with Brittney Griner and the Phoenix Mercury on potential new travel options, including charter flights, after the basketball star was harassed when going through a Dallas airport last week.Iowa's Supreme Court voted 3-3 to keep abortion legal in the state, upholding an earlier 2019 ruling that had blocked a law banning most abortions.The bodies of 41 people, including 38 students, were recovered after an attack by suspected rebels on a secondary school near the border with Congo, officials said.A sweltering heat wave is hitting Texas, including areas ravaged by tornadoes days ago, and parts of the south this holiday weekend.Police say 15 people were injured after a mass transit bus crashed with two cars in Baltimore.The American who died after allegedly being pushed from a cliff near a castle in Germany has been named as 21-year-old Eva Liu. The young woman traveled to the country with Kelsey Chang, 22, following their May graduation from the University of Illinois Urbana-Champaign. ![]() ![]() ![]() Your right to use the work may be terminated if you fail to comply with these terms. You may use the work for your own noncommercial and personal use any other use of the work is strictly prohibited. Except as permitted under the Copyright Act of 1976 and the right to store and retrieve one copy of the work, you may not decompile, disassemble, reverse engineer, reproduce, modify, create derivative works based upon, transmit, distribute, disseminate, sell, publish or sublicense the work or any part of it without McGraw-Hill Education’s prior consent. Use of this work is subject to these terms. This is a copyrighted work and McGraw-Hill Education and its licensors reserve all rights in and to the work. The series editor was Grace Freedson, and the project editor was Del Franz. McGraw-Hill Education is not associated with any product or vendor mentioned in this book.ĪP, Advanced Placement Program, and College Board are registered trademarks of the College Board, which was not involved in the production of, and does not endorse, this product. All other trademarks are the property of their respective owners. To contact a representative, please visit the Contact Us page at Trademarks: McGraw-Hill Education, the McGraw-Hill Education logo, 5 Steps to a 5, and related trade dress are trademarks or registered trademarks of McGraw-Hill Education and/or its affiliates in the United States and other countries and may not be used without written permission. McGraw-Hill Education eBooks are available at special quantity discounts to use as premiums and sales promotions or for use in corporate training programs. ![]() Where such designations appear in this book, they have been printed with initial caps. Rather than put a trademark symbol after every occurrence of a trademarked name, we use names in an editorial fashion only, and to the benefit of the trademark owner, with no intention of infringement of the trademark. The material in this eBook also appears in the print version of this title: ISBN: 978-1-25-986318-9, MHID: 1-25-986318-2.Īll trademarks are trademarks of their respective owners. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher. Copyright © 2017 by McGraw-Hill Education. ![]() ![]() ![]() She has more personality than Tomoya gives her credit for. Yeah, how dare you not break school property, Megumi! He even wants her to bust down the door in anger instead of working to fix it. I guess Tomoya wants her to protest in tears before running away. ![]() She agrees to help him out and is willing to try out dating sims and anime. We’re supposed to feel sorry for him? Tomoya also mentions Megumi is a pushover, but he should be grateful she hasn’t fled or spread rumors about him. Well, if a guy in my class didn’t even recognize me and then told me later I was cute but had no personality, I probably wouldn’t worry about him taking a romantic interest in me either. Meanwhile, Tomoya is almost depressed by the fact Megumi isn’t acting all cute and embarrassed around him. Most notably, Megumi isn’t Tomoya’s girlfriend, and she really doesn’t have an issue with his hobbies. The summary makes it sound a bit like Comic Party and other stories where one person is an otaku and their boyfriend/girlfriend is a “normie”. ![]() (It’s based on a light novel, but I can’t compare the manga to the original.) How to Raise a Boring Girlfriend is certainly not a gut-bursting comedy, but it’s also not an introspective look at otaku life. Seriously, I have no idea what the point of this manga is. So he’s going to show her how anime characters act to teach Megumi how to stand out, and then this will improve the game he’s going to make. According to Tomoya, otaku extraordinaire, being plain is an attribute, but Megumi is “dead of character”. Then Tomoya gets the idea that Megumi could be used as the basis for his game heroine. Well, it turns she’s an almost-invisible, background-character-like classmate. Tomoya thinks he may have met the girl of his dreams. The title sounds like a guy wants to keep his girlfriend boring to prevent any future love triangles. I really didn’t know anything about this series before I started reading it. It took me about a half a volume to realize How to Raise a Boring Girlfriend was not for me. Inspiration strikes when he has a destined encounter, but his partner turns out to be the most boring girl in school! Tomoya believes he’s on to something, and now all he needs is his two sort-of friends with secret hobbies to turn Megumi into a game heroine. Tomoya dreams of making the best dating sim ever. MARUTO Fumiaki (story), MORIKI Takeshi (art), MISAKI Kurehito (character design)ģ Volumes (ongoing) of 11 Volumes (ongoing) ![]() ![]() ![]() Continued abuse of our services will cause your IP address to be blocked indefinitely. Please fill out the CAPTCHA below and then click the button to indicate that you agree to these terms. If you wish to be unblocked, you must agree that you will take immediate steps to rectify this issue. If you do not understand what is causing this behavior, please contact us here. If you promise to stop (by clicking the Agree button below), we'll unblock your connection for now, but we will immediately re-block it if we detect additional bad behavior. Clandestiny walkthrough - solution - by Dave Melanson from The Spoiler Centre collection of faqs for games. Overusing our search engine with a very large number of searches in a very short amount of time.Using a badly configured (or badly written) browser add-on for blocking content.Running a "scraper" or "downloader" program that either does not identify itself or uses fake headers to elude detection.Using a script or add-on that scans GameFAQs for box and screen images (such as an emulator front-end), while overloading our search engine.There is no official GameFAQs app, and we do not support nor have any contact with the makers of these unofficial apps. Clandestiny: The Official Strategy Guide, 05/25/97 Darkseed 2 Hints MDK Trainer Download Site Realms of the Haunting Hints, 5/21/97. Clandestiny Clandestiny is a puzzle adventure game that takes place in Scotland. Doubtless, using this walkthrough will spoil some of the fun of figuring. In this animated tale of ghosts and family redemption set in Scotland, you control the actions and exploits of Andrew MacPhiles as he takes possession of an inherited castle - an isolated, dark, dank and creepy place filled with 12 spirits from the long and cowardly line of his ancestors. Clock Tower Dungeon Endgame Maps Secret Passages MacPhiles Ghosts MacPhiles Crest Scottish Cookbook Review In Trilobyte's Clandestiny, you control the fate of one Andrew MacPhiles, who has recently inherited a Scottish castle full of ghosts, and an earldom along with it. Clandestiny was made in 'Adventure' genre. This game has been published by Trilobyte at Oct 15, 1996. ZIP Clandestiny Walkthrough DAG179.EXE Daggerfall patch to V1.79 DF-C131.ZIP Candi v1.31 Registered DR-CHTS.ZIP Death Rally cheat codes. Continued use of these apps may cause your IP to be blocked indefinitely. What follows is a complete solution for the game, with solutions to all of the puzzles. This page contains Clandestiny cheats, hints, walkthroughs and more for PC. This triggers our anti-spambot measures, which are designed to stop automated systems from flooding the site with traffic. Some unofficial phone apps appear to be using GameFAQs as a back-end, but they do not behave like a real web browser does. Clandestiny (part 01 game walkthrough) 123Pazu 18.Using GameFAQs regularly with these browsers can cause temporary and even permanent IP blocks due to these additional requests. On a lonely, desolate piece of land at the edge of the Scottish Isles, where no man of right mind would build a home, stands the infamous Castle MacPhiles. If you are using the Brave browser, or have installed the Ghostery add-on, these programs send extra traffic to our servers for every page on the site that you browse, then send that data back to a third party, essentially spying on your browsing habits. Please remember to bookmark this page and come back for Clandestiny guides and walkthroughs which will be located here as soon as we get any Clandestiny walkthroughs.We strongly recommend you stop using this browser until this problem is corrected. The latest version of the Opera browser sends multiple invalid requests to our servers for every page you visit.The most common causes of this issue are: There aren't any feelies in a torrent file so what's the point?Īdvertising - Don't advertise your games in this subreddit unless they are of the Adventure Game genre in some shape or form.Your IP address has been temporarily blocked due to a large number of HTTP requests. Spoiler tags must be used! Yes, even if the spoiler is for a 20 year old title.Įxample: (/spoiler)] Despite rumours to the contrary, the genre is decidedly not dead. They are often linear but many modern titles have experimented with branching paths, multiple endings, and innovative gameplay elements, such as Resonance's short-term and long-term memory feature. CLANDESTINELY English meaning - Cambridge Dictionary Meaning of clandestinely in English clandestinely adverb uk / klændes.tn.li / us / klændes.tn. Gameplay usually consists of dialogue and environment-based narratives explored via solving puzzles. What's an adventure game?Īdventure games are typically story-driven titles in which the player assumes the role of the protagonist. Subreddit for the discussion and appreciation of the adventure game genre. ![]() ![]() ![]() The course comes with the wide range of sample documents and photographs you will need to practice all of InDesign’s important features and, by the end of the course, you will have worked with a variety of different documents, and you will be using InDesign like a professional, producing documents like the brochure pictured on the right. InDesign has everything you need to create and publish stunning books, digital magazines, eBooks, posters, interactive PDFs and much more.įor the absolute beginner, the course is self-paced and highly-practical, teaching you the fundamental concepts and features through hands-on exercises and assignments and, if you have previous InDesign experience, we investigate and try out many advanced features, such as interactive presentations, nested styles, tables of content, anchored objects, and paths. With InDesign, you can create beautiful graphic designs with typography and imagery from Adobe Stock and quickly share content and feedback in PDF. If you wish to become proficient in InDesign’s wide range of design tools or wish to undertake a course of study to prepare you for the Adobe Certified Professional in “Print & Digital Media Publication Using InDesign CC” examination, an industry-recognised qualification, then this is the course for you.Īdobe’s InDesign CC is the world’s leading document design application, setting the standard for industry-leading layout and page design software for print and digital media. ![]() The Adobe InDesign CC Print and Digital Media Publication Essentials Course follows the syllabus for the corresponding Adobe Certified Professional examination (Formally Adobe Certified Associate / ACA) and, as well as being suitable for beginners, who wish to become proficient in InDesign’s wide variety of document design and publication features, the course can be used both as a primer or as a refresher course prior to taking the Certified Professional examination. ![]() ![]() ![]() Todoist can do everything from basic task management to more complex project management. This makes it easy to get your tasks into Todoist and then get reminders at just the right time.Ĥ – Todoist is simple, with advanced features for power users Todoist integrates with Gmail and Outlook, Google Calendar, Siri & Alexa, Zapier, and a ton of other apps through their API. No other task manager integrates with as many other tools as Todoist. This is a huge advantage because it allows Todoist to be used in conjunction with the tools you’re already using. Todoist also makes it easy to stay focused and plan ahead with the Today and Upcoming views in addition to the integration with Google Calendar.ģ – Todoist has more integrations than any other task managerĪs I said above, Todoist has apps for all the major platforms. You can quickly and easily add tasks, set due dates, assign labels, and more. The Todoist interface is clean, user-friendly, and easy to navigate. But if you’re looking for a more complex task management system, Todoist can handle that too.Īnd because Todoist is available on so many platforms, you can access your tasks from anywhere.Ģ – The interface is clean and user-friendly If all you need is a simple to-do list app, Todoist will work great. This is hugely important because it means that Todoist can easily fit into your existing workflow, no matter what that looks like. Whether you’re at your computer or on the go, Todoist will be there for you. Todoist is available on practically any device you could want to use it on (iOS, Android, macOS, Windows, web). Todoist also offers a Business plan for teams.Ĭlick Here to Get 2 Free Months of Todoist Pro What Is So Good About Todoist? The Pro plan includes features like labels, filters, file attachments, and reminders. Todoist pricing starts with the Free plan which includes basic features like task management and due dates. Todoist is available on all major platforms (iOS, Android, macOS, Windows, web), as well as plugins for Gmail and Outlook. ![]() You can also easily share tasks with others and collaborate on projects. Todoist also has key features like labels and filters so you can organize your tasks in any way you want and display the right tasks at the right time. With Todoist, you can create tasks and subtasks, and set priorities, due dates, and recurring dates. Todoist can be used for work, school, or personal projects. Todoist is a to-do list and task manager app that helps you get organized and achieve peace of mind. It’s not enough to send my kids to college, but it helps me keep my servers running. It does mean that if you register for Todoist through my affiliate link you’ll get two months of Pro for free and I’ll earn a commission if you decide to subscribe. This full review will help you decide if Todoist is right for you!įirst off a disclaimer: I am an affiliate for Todoist because I’ve been using it since 2015 and absolutely love it. But, is it the best for you? In this review, I’ll share the good, the bad, and my experience with Todoist in terms of features, price, and ease of use. One of the most popular task management apps is Todoist. Most of the specialized tools I used before I came to Obsidian lack a wiki that I can refer to later, which has been my No.1 need after realizing I'd almost forgotten all things I'd learned during the past 2 years from my work projects.If you’re looking for a great way to manage your tasks and increase your productivity, there are a lot of options. I mean, of course you can literally write almost anything in Obsidian but tools on that level would be a pain in the ass to write out and it might not be as efficient either.įor me I only have needs for small projects which usually involve lots of note-taking, concept building, and code snippet collection, so Obsidian is a suitable tool for my project and knowledge management. those that also has a need for managing people or collaboration (for example I wouldn’t consider making Obsidian a collaborative team wiki) there are lots of sophisticated tools on the market. I only use Obsidian to prepare projects like writing a paper/preparing for a lecture/conducting an experiment. ![]() ![]() Thomas plots a unique way to handle Michael, while Christie makes a decision. A group of young adults, who meet online, get a hold of a cult underground graphic novel, which not only pins them as a target of a shadowy deep state organization, but also burdens them with the dangerous task of saving the world. Septem48min 16+ A clue in Utopia leads Jessica and the crew to a mysterious new ally. ![]() John Cusack Faces The End of the World in Gillian Flynns Utopia: Watch The. Even after 47 years since his first film, Hollywoods most-favourite actor, John Cusack could easily turn an average role into something that we just cant get. Amazon Primes original drama Utopia, starring John Cusack, has been canceled following its first season. “But it’s a dystopian theme, and it’s also about the globe is hurtling towards climate extinction with global warming and nuclear war and all these grave existential threats that we face - so there’s no doubting that that was part of the theme. With John Cusack, Ashleigh LaThrop, Dan Byrd, Desmin Borges. New York Comic Con Schedule: Every TV and Movie Panel, from Walking Dead. So, I mean, the show wasn’t made to exploit any of those realities,” he says. Science is often seen as a liberal conspiracy, and it’s super important, to me, to support our scientists.”Ĭusack says the real-life parallels are “surreal.” “Of course, nobody wants the west to be on fire, or be to living through a pandemic. “This is why science has become so important in this day and age - because scientists can be vilified. “ doing the work with the test tubes and the funding, who just cares about the data and doing things right,” says Wilson. ![]() If you can grind your way through the blood and horror, this Gillian Flynn adaptation occasionally makes its. But at least its not a mass appeal US remake. Wilson plays Michael Stearns, a virologist whose stick-to-the-data steadfastness in combating a disease outbreak runs up against Christie’s (Cusack) slick corporate swagger. A review of Utopia, starring Rainn Wilson, Desmin Borges, Sasha Lane, and John Cusack. ![]() The show’s dystopian storylines, which include corporate manipulation, a burgeoning pandemic and questioning the validity of science, feel incredibly relevant, says Rainn Wilson. It centers on a group of comic book enthusiasts who track down a rare edition of a beloved graphic novel that has predicted worldwide epidemics, only to uncover even more intricate and darker conspiracies. There certainly is enough bad karma to go around in “Utopia,” created by Gillian Flynn and adapted from a 2013 British sci-fi drama of the same name. Utopia is based on a 2013-14 British series about a group of comic book fans who accidentally have to save the world when they get possession of a sought-after comic manuscript. ![]() |